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| Academics > College > College of Medicine |
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Mediacl science |
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For detailed faculty profile, please log on to the Portal System.
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Name |
LEE, JA KYEOUNG |
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Department |
School of Medicine |
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E-mail |
jklee@inha.ac.kr |
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Tel |
890-0913 |
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Date |
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Position |
Professor |
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Laboratory |
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Major |
Neurobiology |
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 Degree thesis |
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| Major scientific journals |
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- Gene Knockdown in the Olfactory Bulb, Amygdala, and Hypothalamus by Intranasal siRNA Administration, 대한해부학회지, 42권 4호, pp285~291, 2009.
- aB-crystallin suppresses oxidative stress-induced astrocyte apoptosis by inhibiting caspase 3 activation, NEUROSCIENCE RESEARCH, 64, pp355~361, 2009.
- Fluoxetine attenuates kainic acid-induced neuronal cell death in the mouse hippocampus., BRAIN RESEARCH, 1281, pp108~116, 2009.
- Fluoxetine affords robust neuroprotection in the postischemic brain via its anti-inflammatory effect, JOURNAL OF NEUROSCIENCE RESEARCH, 64, pp355~361, 2009.
- Behavioral stress acclerates plaque pathogenesis in the brain of Tg2576 via generation of metabolic oxidative stress, JOURNAL OF NEUROCHEMISTRY, 108, pp165~175, 2009.
- Adenyryl clclase- 5 activity in nucleus accumbens regulates anxiety-related behavior, JOURNAL OF NEUROCHEMISTRY, 107, pp106~115, 2008.
- Extracellular HMGB1 Released after Zinc-treatmentInduces Neuronal Death in Primary CorticalCultures, 대한해부학회지, 41권 1호, pp89~96, 2008.
- Induction and subcellular localization of High Mobility Group Box 1 (HMGB1), JOURNAL OF NEUROSCIENCE RESEARCH, 86, pp1125~1131, 2008.
- New peptidic neuroprotectants against NMDA neurotoxicity: Syntheses and biological evaluations of linear complestatin analogs, LETTERS IN DRUG DESIGN & DISCOVERY, 5, pp104~107, 2008.
- LEDGF binding to Stress response element increases 꺫B-crystallin expression in astrocytes with oxidative stress, NEUROSCIENCE LETTERS, 435, pp131~136, 2008.
- mORPHOGENIC LUNG DEFECTS OF jsap1-DEFICIENT EMBRYOS PROCEEDS VIA THE DISRUPTIONS OF THE NORMAL EXPRESSIONS OF CYTOSKELETAL AND CHAPERONE PROTEINS, PROTEOMICS, 8, pp1071~1080, 2008.
- NO-induced downregulation of HSP10 and HSP60 expression in the postischemic brain, JOURNAL OF NEUROSCIENCE RESEARCH, 85권 6호, pp1252~1259, 2007.
- SP1 Mediates IFNγ-induced TIMP-1 Transctription in C6 Astroglioma Cells, 대한해부학회지, 40권 2호, pp77~83, 2007.
- Interferon-gamma-induced expressions of heat shock protein 60 and heat shock protein 10 in C6 astroglioma cells: identification of the signal transducers and activators of transcription 3-binding site in bidirectional promoter, NEUROREPORT, 18권 4호, pp385~389, 2007.
- Ethyl pyruvate attenuates kainic acid-induced neuronal cell death in the mouse hippocampus, JOURNAL OF NEUROSCIENCE RESEARCH, 84, pp1505~1511, 2006.
- Enhanced transfection of primary cortical cultures using arginine-grafted PAMAM dendrimer, PAMAM-Arg, JOURNAL OF CONTROLLED RELEASE, 114, pp110~117, 2006.
- Adenylyl Cyclase-5 is an Essential Mediator of Morphine Action, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 103, pp3908~3913, 2006.
- Stimulus dependent-differerntial regulation of JNK1 and JNK3 by JIP1 scaffold proein in human neuroblastoma, SH-SY5Y, 대한해부학회지, 39, pp47~53, 2006.
- HMGB1, a novel cytokine-like mediator linking acute neuronal death and delayed neuroinflammation in the postischemic brain, JOURNAL OF NEUROSCIENCE, 26, pp6413~6421, 2006.
- Anti-inflammatory mechanism is involved in ethyl pyruvate-mediated efficacious neuroprotection in the postischemic brain, BRAIN RESEARCH, 1060, pp188~192, 2005.
- Inhibition of the cerebral ischemic injury by ethyl pyruvate with a wide therapeutic window, STROKE, 36, pp2238~2243, 2005.
- Co-induction of B-crystallin and MAPKAP-K2 in Astrocytes in the Penumbra Following Transient Focal Cerebral Ischemia, EXPERIMENTAL BRAIN RESEARCH, 163, pp421~429, 2005.
- The axon guidance of the telencephalic commissures of the JSAP-1 deficient brain was partially rescued by the transgenic expression of JIP1, DEVELOPMENTAL BIOLOGY, 277, pp184~199, 2005.
- Enhanced transfection efficiency of PAMAM dendrimer by surface modification with L-arginine, JOURNAL OF CONTROLLED RELEASE, 99, pp445~456, 2004.
- COX-2 regulates the insulin-like growth factor I-induced potentiation of Zn2+-toxicity in primary cortical culture, MOLECULAR PHARMACOLOGY, 66, pp368~376, 2004.
- p38 MAPK의 억제를 통한 간질에 의한 신경세포 손상 억제 효과, BRAIN RESEARCH, 1007, pp188~191, 2004.
- Delayed genomic responses to transient middle cerebral artery occlusion in rat, JOURNAL OF NEUROCHEMISTRY, 89, pp1271~1282, 2004.
- Protective effects of extracellular glutathione against Zn2+-induced cell death in vitro and in vivo., JOURNAL OF NEUROSCIENCE RESEARCH, 74, pp736~743, 2003.
- Chronic restraint stress massively alters the expression of genes important for lipid metabolism and detoxification in liver., TOXICOLOGY LETTERS, 146, pp49~63, 2003.
- Phospho-JNK repression and infarct volume in ischemic brain of JIP1-deficient mice, JOURNAL OF NEUROSCIENCE RESEARCH, 74, pp326~332, 2003.
- JNK pathway is required for retinoic acid-induced neurite outgrowth of human neuroblastoma, SH-SY5Y, NEUROREPORT, 14, pp941~945, 2003.
- Dynamic expression of p38b MAPK in neurons and astrocytes after transient focal ischemia, BRAIN RESEARCH, 976, pp120~124, 2003.
- Administration of the p38 MAPK inhibitor SB203580 affords brain protection with a wide therapeutic window against focal ischemic insult, JOURNAL OF NEUROSCIENCE RESEARCH, 73, pp537~544, 2003.
- Delayed and differential induction of p38 MAPK isoforms in microglia and astrocytes in the brain after transient global ischemia, MOLECULAR BRAIN RESEARCH, 107, pp137~144, 2002.
- Impaired d2 dopamine receptor function in mice lacking type 5 adenylyl cyclase, JOURNAL OF NEUROSCIENCE, 22(18), pp7931~7940, 2002.
- Delayed induction of p38 MAPK in reactive astrocytes in the brain of mice after KA-induced seizure, MOLECULAR BRAIN RESEARCH, vol. 94, NO 1-2, pp157~165, 2001.
- Delayed induction of aB-crystallinin activated glia cells in hippocampus in kainic acid-treated mouse brain, JOURNAL OF NEUROSCIENCE RESEARCH, vol.65, pp425~431, 2001.
- Identification of aB-crystallin in astrocytes in the brain after transient global ischemia, Experimental Neurobiology, vol. 10, pp57~62, 2001.
- Induction of aB-crystallin in the hippocampus of KA-treated mouse brain, 대한해부학회지, 34권, 2호, pp123~130, 2001.
- Constitutive Activity and Diffetential lOCALIZATION OF p38a and p38b MAPKs in Adult Brain, JOURNAL OF NEUROSCIENCE RESEARCH, Vol. 60, pp623~631, 2000.
- Expression of NeuroD/BETA2 in mitotic and postmitotic neuronal cells during the development of nervous system, DEVELOPMENTAL DYNAMICS, Vol. 217, pp361~367, 2000.
- Distint localization of SAPK isoforms in neurons of adult mouse brain implies multiple signaling modes of SAPK pathway, Molecular Brain Research, Vol. 70, pp116~124, 1999.
- Molecular cloning od multiple splicing variants of JIP-1 preferentially expressed in brain, J. Neurochem., Vol. 72, No. 4, pp1335~1343, 1999.
- Dynamic expression of SEK1 suggests multiple roles of the gene during embryogenesis and in adult brain of mice, Molecular Brain Research, Vol.66 , pp133~140, 1999.
- High levels of expression and high basal activity of p38 kinase in adult mouse brain, Experimental Neurobiology, Vol. 7, No. 2, ppinpress, 1998.
- Molecular mechanism of cell fate determination for neuron vs. glia, Current Trends in Neuroscience, 6권 1호, pp99~114, 1998.
- Drosophila sanpodo gene controls sibling cell fate by mediating Notch signalling, and encodes a tropomodulin homolog, an actin/myosin associated protein, Development, vol. 125, No.10, pp1845~1856, 1998.
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| Major publications |
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| patent |
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글루코사민을 유효성분으로 포함하는 염증에 의한 뇌손상 예방 및 치료용 조성물, 2008
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에틸피루베이트를 유효성분으로 포함하는 간질성 발작에 의한 신경세포 손상예방 및 치료용 약학적 조성물, 2008
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뇌경색 영역의 부피 계산에 의한 뇌경색 치료물질의 스크리닝 방법, 2008
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알킬피루베이트를 유효성분으로 함유하는 신경보호제(Neuroprotective agent containing alkylpyruvate), 2007
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알킬피루베이트를 유효성분으로 함유하는 신경보호제, 2004
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3331, 2002
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마우스 skip, 1999
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